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In vitro studies document interactions with VEGFR2, EGFR, and FAK phosphorylation cascades, with modulation of pro-angiogenic signalling networks
Studies have shown that several DNMT inhibitors including azacitidine, decitabine, procainamide, hydralazine, and epigallocatechin-3-gallate are applied in animals, which show excellent efficacies via decreasing pro-inflammatory cytokines ( i.e
As a result, researchers can evaluate with a more complete research model rather than focusing on a single pathway
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